Home     Articles      Contact us     Labrador Retrievers     Papillons     Miniature Horse  

Centronuclar Myopathy  =  CNM

CNM (Centronuclear Myopathy)  is something that no breeder would like to have happen in their puppies and something that you can eliminate via an easy dna test. If a breeder breeds a carrier to a carrier, puppies with CNM can be produced. It just takes testing your breeding dogs to be sure you never produce this problem. Breeders should be testing their dogs. Originally called Labrador Muscular Myopathy or Hereditary Myopathy of the Labrador Retriever (HMLR) due to it being breed specific to labradors. It is a hereditary disease where the muscles of the Labrador do not develop properly.   Affected pups are obvious by the time they are between three and six months of age.  The pup will begin to stumble and fall when trying to walk. There are difficulties in swallowing since the muscles in the esophagus are often affected.  There is no cure for the disease.  CNM is a simple autosomal recessive.  Please go to www.labradorcnm.com and look at the Genetics link in the left menu for charts on breeding.   Consider the charts before planning a breeding.

This dog in the video to the left is NOT our dog.


To the left is a video that shows the outcome of an affected dog. The lab in the video below is not our dog. This was a video from youtube that gave an example so viewers could see what the syndrome looks like.

We have tested our Labrador Retrievers that parent our litters. Both Nina and Goldie tested clear!

Diagnosing CNM Affected, Carrier, and Clean Labrador Retrievers.
The CNM DNA test, available at www.labradorcnm.com, is highly reliable in identifying the disease. It can determine affected, carriers, and clean CNM Labradors.    It is inexpensive and involves a non-painful collection of cells from the inside of the canine’s cheek.   The owner can easily do the test themselves, or can choose to go to a veterinarian.  The CNM Project provides kits and e-forms with very specific easy directions.  The only other way to determine if a parent in a Labrador litter is a known carrier would be if an affected pup had been produced.  At one time biopsies were also used, but these have been abandoned as a method since they do not identify carriers and are expensive and invasive.

For questions and further information on CNM, write to info@labradorcnm.com or browse the CNM web site at www.labradorcnm.com 


Click here for Nina's CNM results                    

Click here for Goldie's CNM results                 

    Click here to read about EIC in Labradors.

Click here to got back to "Health Concerns in Labrador Retrievers"

Home     Articles      Contact us     Labrador Retrievers     Papillons     Miniature Horses